A ribonuclease coordinates siRNA amplification and mRNA cleavage during RNAi

Effective silencing by RNA-interference (RNAi) depends on mechanisms that amplify and propagate the silencing signal. In some organisms, small-interfering (si) RNAs are amplified from target mRNAs by RNA-dependent RNA polymerase (RdRP). Both RdRP recruitment and mRNA silencing require Argonaute prot...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Tsai, Hsin-Yue, Chen, Chun-Chieh G., Conte, Darryl, Moresco, James J., Chaves, Daniel A., Mitani, Shohei, Yates, John R., Tsai, Ming-Daw, Mello, Craig C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318647/
https://ncbi.nlm.nih.gov/pubmed/25635455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.010
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk