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Opportunities and limits of the one gene approach: the ability of Atoh1 to differentiate and maintain hair cells depends on the molecular context

Atoh1 (Math1) was the first gene discovered in ear development that showed no hair cell (HC) differentiation when absent and could induce HC differentiation when misexpressed. These data implied that Atoh1 was both necessary and sufficient for hair cell development. However, other gene mutations als...

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Detaylı Bibliyografya
Yayımlandı:Front Cell Neurosci
Asıl Yazarlar: Jahan, Israt, Pan, Ning, Fritzsch, Bernd
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318345/
https://ncbi.nlm.nih.gov/pubmed/25698932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00026
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