Mosaic mice with teratocarcinoma-derived mutant cells deficient in hypoxanthine phosphoribosyltransferase

Mutagenized stem cells of a cultured mouse teratocarcinoma cell line were selected for resistance to the purine base analog 6-thioguanine. Cells of a resistant clone were completely deficient in activity of the enzyme hypoxanthine phosphoribosyltransferase (HPRT, IMP:pyrophosphate phosphoribosyltran...

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Bibliografski detalji

Izdano u:	Proc Natl Acad Sci U S A
Glavni autori:	Dewey, Michael J., Martin, David W., Martin, Gail R., Mintz, Beatrice
Format:	Artigo
Jezik:	Inglês
Izdano:	National Academy of Sciences 1977
Teme:	Biological Sciences: Cell Biology
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431809/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/271982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.12.5564
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