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DSE-FRET: A new anticancer drug screening assay for DNA binding proteins
Nuclear factor-κB (NF-κB) is a key regulator of cancer progression and the inflammatory effects of disease. To identify inhibitors of DNA binding to NF-κB, we developed a new homogeneous method for detection of sequence-specific DNA-binding proteins. This method, which we refer to as DSE-FRET, is ba...
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| Veröffentlicht in: | Cancer Sci |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Publishing Ltd
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317927/ https://ncbi.nlm.nih.gov/pubmed/24724610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12420 |
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