DSE-FRET: A new anticancer drug screening assay for DNA binding proteins

Nuclear factor-κB (NF-κB) is a key regulator of cancer progression and the inflammatory effects of disease. To identify inhibitors of DNA binding to NF-κB, we developed a new homogeneous method for detection of sequence-specific DNA-binding proteins. This method, which we refer to as DSE-FRET, is ba...

Full description

Saved in:
Bibliographic Details
Published in:Cancer Sci
Main Authors: Miyagi, Toru, Shiotani, Bunsyo, Miyoshi, Ryuya, Yamamoto, Takuya, Oka, Takanori, Umezawa, Kazuo, Ochiya, Takahiro, Takano, Mikihisa, Tahara, Hidetoshi
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317927/
https://ncbi.nlm.nih.gov/pubmed/24724610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12420
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items