Suppression of Tregs by anti-glucocorticoid induced TNF receptor antibody enhances the antitumor immunity of interferon-α gene therapy for pancreatic cancer

We have reported that interferon (IFN)-α can attack cancer cells by multiple antitumor mechanisms including the induction of direct cancer cell death and the enhancement of an immune response in several pancreatic cancer models. However, an immunotolerant microenvironment in the tumors is often resp...

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Publicat a:Cancer Sci
Autors principals: Aida, Kouichirou, Miyakawa, Reina, Suzuki, Koji, Narumi, Kenta, Udagawa, Takeshi, Yamamoto, Yuki, Chikaraishi, Tatsuya, Yoshida, Teruhiko, Aoki, Kazunori
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317823/
https://ncbi.nlm.nih.gov/pubmed/24289533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12332
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