Preimmunization of donor lymphocytes enhances antitumor immunity of autologous hematopoietic stem cell transplantation

Lymphopenia-induced homeostatic proliferation (HP) of T cells following autologous hematopoietic stem cell transplantation (HSCT) skews the T-cell repertoire by engaging tumor-associated antigens (TAAs), leading to an induction of antitumor immunity. Here, as the tumor-reactive lymphocytes preferent...

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Autori principali: Suzuki, Koji, Aida, Kouichirou, Miyakawa, Reina, Narumi, Kenta, Udagawa, Takeshi, Yoshida, Teruhiko, Ohshima, Yusei, Aoki, Kazunori
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
Soggetti:
Cancer Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892795/
https://ncbi.nlm.nih.gov/pubmed/24403229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.117
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