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A Neuroprotective Function of NSF1 Sustains Autophagy and Lysosomal Trafficking in Drosophila

A common feature of many neurodegenerative diseases is the accumulation of toxic proteins that disrupt vital cellular functions. Degradative pathways such as autophagy play an important protective role in breaking down misfolded and long-lived proteins. Neurons are particularly vulnerable to defects...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Babcock, Daniel T., Shen, Wei, Ganetzky, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317658/
https://ncbi.nlm.nih.gov/pubmed/25519897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.172403
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