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Transcellular spreading of huntingtin aggregates in the Drosophila brain

A key feature of many neurodegenerative diseases is the accumulation and subsequent aggregation of misfolded proteins. Recent studies have highlighted the transcellular propagation of protein aggregates in several major neurodegenerative diseases, although the precise mechanisms underlying this spre...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Babcock, Daniel T., Ganetzky, Barry
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593132/
https://ncbi.nlm.nih.gov/pubmed/26351672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516217112
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