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Transcellular spreading of huntingtin aggregates in the Drosophila brain

A key feature of many neurodegenerative diseases is the accumulation and subsequent aggregation of misfolded proteins. Recent studies have highlighted the transcellular propagation of protein aggregates in several major neurodegenerative diseases, although the precise mechanisms underlying this spre...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Babcock, Daniel T., Ganetzky, Barry
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593132/
https://ncbi.nlm.nih.gov/pubmed/26351672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516217112
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