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DNA sequencing with chain-terminating inhibitors

A new method for determining nucleotide sequences in DNA is described. It is similar to the “plus and minus” method [Sanger, F. & Coulson, A. R. (1975) J. Mol. Biol. 94, 441-448] but makes use of the 2′,3′-dideoxy and arabinonucleoside analogues of the normal deoxynucleoside triphosphates, which...

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Bibliografiske detaljer
Main Authors: Sanger, F., Nicklen, S., Coulson, A. R.
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC431765/
https://ncbi.nlm.nih.gov/pubmed/271968
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