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DNA sequencing with chain-terminating inhibitors

A new method for determining nucleotide sequences in DNA is described. It is similar to the “plus and minus” method [Sanger, F. & Coulson, A. R. (1975) J. Mol. Biol. 94, 441-448] but makes use of the 2′,3′-dideoxy and arabinonucleoside analogues of the normal deoxynucleoside triphosphates, which...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Sanger, F., Nicklen, S., Coulson, A. R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1977
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/271968/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.12.5463
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