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PINK1 Kinase Catalytic Activity Is Regulated by Phosphorylation on Serines 228 and 402
Mutations in the PINK1 gene cause early-onset recessive Parkinson disease. PINK1 is a mitochondrially targeted kinase that regulates multiple aspects of mitochondrial biology, from oxidative phosphorylation to mitochondrial clearance. PINK1 itself is also phosphorylated, and this might be linked to...
Uloženo v:
| Vydáno v: | J Biol Chem |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317039/ https://ncbi.nlm.nih.gov/pubmed/25527497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.620906 |
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