Amitriptyline Improves Motor Function via Enhanced Neurotrophin Signaling and Mitochondrial Functions in the Murine N171-82Q Huntington Disease Model

Huntington disease (HD) is a neurodegenerative disorder characterized by progressive motor impairment and cognitive alterations. Hereditary HD is primarily caused by the expansion of a CAG trinucleotide repeat in the huntingtin (Htt) gene, which results in the production of mutant huntingtin protein...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cong, Wei-Na, Chadwick, Wayne, Wang, Rui, Daimon, Caitlin M., Cai, Huan, Amma, Jennifer, Wood, William H., Becker, Kevin G., Martin, Bronwen, Maudsley, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317004/
https://ncbi.nlm.nih.gov/pubmed/25505248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.588608
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados