Euglycemic Agent-mediated Hypothalamic Transcriptomic Manipulation in the N171–82Q Model of Huntington Disease Is Related to Their Physiological Efficacy

Our aim was to employ novel analytical methods to investigate the therapeutic treatment of the energy regulation dysfunction occurring in a Huntington disease (HD) mouse model. HD is a neurodegenerative disorder that is characterized by progressive motor impairment and cognitive alterations. Changes...

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Autors principals: Martin, Bronwen, Chadwick, Wayne, Cong, Wei-na, Pantaleo, Nick, Daimon, Caitlin M., Golden, Erin J., Becker, Kevin G., Wood, William H., Carlson, Olga D., Egan, Josephine M., Maudsley, Stuart
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Neurobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442511/
https://ncbi.nlm.nih.gov/pubmed/22822065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.387316
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