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Euglycemic Agent-mediated Hypothalamic Transcriptomic Manipulation in the N171–82Q Model of Huntington Disease Is Related to Their Physiological Efficacy

Our aim was to employ novel analytical methods to investigate the therapeutic treatment of the energy regulation dysfunction occurring in a Huntington disease (HD) mouse model. HD is a neurodegenerative disorder that is characterized by progressive motor impairment and cognitive alterations. Changes...

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Main Authors: Martin, Bronwen, Chadwick, Wayne, Cong, Wei-na, Pantaleo, Nick, Daimon, Caitlin M., Golden, Erin J., Becker, Kevin G., Wood, William H., Carlson, Olga D., Egan, Josephine M., Maudsley, Stuart
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3442511/
https://ncbi.nlm.nih.gov/pubmed/22822065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.387316
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