Identification of the major adducts formed by reaction of benzo(a)pyrene diol epoxide with DNA in vitro.

Covalent binding of the benzo[a]pyrene metabolite (+/-)7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene to calf thymus DNA was investigated. Enzymatic hydrolysis of the carcinogen-modified DNA and subsequent separation via reversed-phase high-pressure liquid chromatograp...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Straub, K M, Meehan, T, Burlingame, A L, Calvin, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1977
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431688/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/271953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.12.5285
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!