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Detection of Somatic TP53 Mutations in Tampons of Patients With High-Grade Serous Ovarian Cancer

OBJECTIVE: To investigate if tumor cells could be detected in the vagina of women with serous ovarian cancer through TP53 analysis of DNA samples collected by placement of a vaginal tampon. METHODS: Women undergoing surgery for a pelvic mass were identified in the gynecologic oncology clinic. They p...

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Publicado en:Obstet Gynecol
Autores principales: Erickson, Britt K., Kinde, Isaac, Dobbin, Zachary C., Wang, Yuxuan, Martin, Jovana Y., Alvarez, Ronald D., Conner, Michael G., Huh, Warner K., Roden, Richard B.S., Kinzler, Kenneth W., Papadopoulos, Nickolas, Vogelstein, Bert, Diaz, Luis A., Landen, Charles N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316672/
https://ncbi.nlm.nih.gov/pubmed/25437714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/AOG.0000000000000484
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