Detection of Somatic TP53 Mutations in Tampons of Patients With High-Grade Serous Ovarian Cancer

OBJECTIVE: To investigate if tumor cells could be detected in the vagina of women with serous ovarian cancer through TP53 analysis of DNA samples collected by placement of a vaginal tampon. METHODS: Women undergoing surgery for a pelvic mass were identified in the gynecologic oncology clinic. They p...

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Detalhes bibliográficos
Publicado no:Obstet Gynecol
Main Authors: Erickson, Britt K., Kinde, Isaac, Dobbin, Zachary C., Wang, Yuxuan, Martin, Jovana Y., Alvarez, Ronald D., Conner, Michael G., Huh, Warner K., Roden, Richard B.S., Kinzler, Kenneth W., Papadopoulos, Nickolas, Vogelstein, Bert, Diaz, Luis A., Landen, Charles N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316672/
https://ncbi.nlm.nih.gov/pubmed/25437714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/AOG.0000000000000484
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