Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V.
Recently, our laboratory described a defect in anticoagulant response to activated protein C (APC). This response, APC resistance, was shown to be inherited and associated with familial thrombophilia. As other possible mechanisms were excluded, APC resistance was hypothesized to be due to deficiency...
Guardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1994
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8108421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1396 |
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