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Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V.

Recently, our laboratory described a defect in anticoagulant response to activated protein C (APC). This response, APC resistance, was shown to be inherited and associated with familial thrombophilia. As other possible mechanisms were excluded, APC resistance was hypothesized to be due to deficiency...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Dahlbäck, B, Hildebrand, B
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1994
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43165/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8108421/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1396
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