Inherited resistance to activated protein C is corrected by anticoagulant cofactor activity found to be a property of factor V.
Recently, our laboratory described a defect in anticoagulant response to activated protein C (APC). This response, APC resistance, was shown to be inherited and associated with familial thrombophilia. As other possible mechanisms were excluded, APC resistance was hypothesized to be due to deficiency...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1994
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43165/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8108421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1396 |
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