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Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

Although patients with thromboembolic disease frequently have family histories of thrombosis, well-defined defects such as inherited deficiencies of anticoagulant proteins are found only in a minority of cases. Based on the hypothesis that a poor anticoagulant response to activated protein C (APC) w...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Dahlbäck, B, Carlsson, M, Svensson, P J
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1993
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45799/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8430067/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.3.1004
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