Manipulating the tumor microenvironment ex vivo for enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy

Eitemau Tebyg

• Continuous 4–1BB co-stimulatory signals for the optimal expansion of tumor-infiltrating lymphocytes for adoptive T-cell therapy
  gan: Chacon, Jessica Ann, et al.
  Cyhoeddwyd: (2013)
• Immediate triggering of 4-1BB co-stimulation during initiation of tumor-infiltrating lymphocyte (TIL) expansion from melanoma tumors accelerates CD8+ T-cell outgrowth and tumor specificity
  gan: Chacon, Jessica, et al.
  Cyhoeddwyd: (2013)
• Triggering co-stimulation directly in melanoma tumor fragments drives CD8(+) tumor-infiltrating lymphocyte expansion with improved effector-memory properties
  gan: Chacon, Jessica Ann, et al.
  Cyhoeddwyd: (2015)
• Co-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy.
  gan: Jessica Ann Chacon, et al.
  Cyhoeddwyd: (2013-01-01)
• Co-Stimulation through 4-1BB/CD137 Improves the Expansion and Function of CD8(+) Melanoma Tumor-Infiltrating Lymphocytes for Adoptive T-Cell Therapy
  gan: Chacon, Jessica Ann, et al.
  Cyhoeddwyd: (2013)