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Stimulation of oxidative phosphorylation by calcium in cardiac mitochondria is not influenced by cAMP and PKA activity

Cardiac oxidative ATP generation is finely tuned to match several-fold increases in energy demand. Calcium has been proposed to play a role in the activation of ATP production via PKA phosphorylation in response to intramitochondrial cAMP generation. We evaluated the effect of cAMP, its membrane per...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Covian, Raul, French, Stephanie, Kusnetz, Heather, Balaban, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315730/
https://ncbi.nlm.nih.gov/pubmed/25178840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2014.08.006
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