β-Adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA

BACKGROUND AND PURPOSE: Genetic approaches have documented protein kinase B (PKB) as a pivotal regulator of heart function. Insulin strongly activates PKB, whereas adrenaline is not considered a major physiological regulator of PKB in heart. In skeletal muscles, however, adrenaline potentiates insul...

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Detalhes bibliográficos
Main Authors: Stuenæs, Jorid T, Bolling, Astrid, Ingvaldsen, Ada, Rommundstad, Camilla, Sudar, Emina, Lin, Fang-Chin, Lai, Yu-Chiang, Jensen, Jørgen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860212/
https://ncbi.nlm.nih.gov/pubmed/20412069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00677.x
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