ApoA-I Milano stimulates lipolysis in adipose cells independently of cAMP/PKA activation

ApoA-I, the main protein component of HDL, is suggested to be involved in metabolic homeostasis. We examined the effects of Milano, a naturally occurring ApoA-I variant, about which little mechanistic information is available. Remarkably, high-fat-fed mice treated with Milano displayed a rapid weigh...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Lindahl, Maria, Petrlova, Jitka, Dalla-Riva, Jonathan, Wasserstrom, Sebastian, Rippe, Catarina, Domingo-Espin, Joan, Kotowska, Dorota, Krupinska, Ewa, Berggreen, Christine, Jones, Helena A., Swärd, Karl, Lagerstedt, Jens O., Göransson, Olga, Stenkula, Karin G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655981/
https://ncbi.nlm.nih.gov/pubmed/26504176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M054767
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