Identification of a functional SNP in the 3′UTR of CXCR2 that is associated with reduced risk of lung cancer

Global changes in gene expression accompany the development of cancer. Thus, inherited variants in microRNA binding sites are likely candidates for conferring inherited susceptibility. Using an in-silico approach, we compiled a comprehensive list of SNPs predicted to modulate microRNA binding in gen...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Ryan, Bríd M., Robles, Ana I., McClary, Andrew C., Haznadar, Majda, Bowman, Elise D., Pine, Sharon R., Brown, Derek, Khan, Mohammed, Shiraishi, Kouya, Kohno, Takashi, Okayama, Hirokazu, Modali, Ramakrishna, Yokota, Jun, Harris, Curtis C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315715/
https://ncbi.nlm.nih.gov/pubmed/25480945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2101
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