Identification of a functional SNP in the 3′UTR of CXCR2 that is associated with reduced risk of lung cancer

Global changes in gene expression accompany the development of cancer. Thus, inherited variants in microRNA binding sites are likely candidates for conferring inherited susceptibility. Using an in-silico approach, we compiled a comprehensive list of SNPs predicted to modulate microRNA binding in gen...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Ryan, Bríd M., Robles, Ana I., McClary, Andrew C., Haznadar, Majda, Bowman, Elise D., Pine, Sharon R., Brown, Derek, Khan, Mohammed, Shiraishi, Kouya, Kohno, Takashi, Okayama, Hirokazu, Modali, Ramakrishna, Yokota, Jun, Harris, Curtis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315715/
https://ncbi.nlm.nih.gov/pubmed/25480945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2101
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