3′ UTR and functional secretor haplotypes in mannose-binding lectin 2 are associated with increased colon cancer risk in African Americans

Because chronic intestinal inflammation is a risk factor for colorectal cancer, we hypothesized that genetic variants of inflammatory mediators, such as mannose-binding lectin 2 (MBL2), are associated with colon cancer susceptibility. Here we report the association of 24 MBL2 single nucleotide polym...

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Main Authors: Zanetti, Krista A., Haznadar, Majda, Welsh, Judith A., Robles, Ana I., Ryan, Bríd M., McClary, Andrew C., Bowman, Elise D., Goodman, Julie E., Bernig, Toralf, Chanock, Stephen J., Harris, Curtis C.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306468/
https://ncbi.nlm.nih.gov/pubmed/22282660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3073
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