Primary Biliary Acids Inhibit Hepatitis D Virus (HDV) Entry into Human Hepatoma Cells Expressing the Sodium-Taurocholate Cotransporting Polypeptide (NTCP)

BACKGROUND: The sodium-taurocholate cotransporting polypeptide (NTCP) is both a key bile acid (BA) transporter mediating uptake of BA into hepatocytes and an essential receptor for hepatitis B virus (HBV) and hepatitis D virus (HDV). In this study we aimed to characterize to what extent and through...

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Publicat a:PLoS One
Autors principals: Veloso Alves Pereira, Isabel, Buchmann, Bettina, Sandmann, Lisa, Sprinzl, Kathrin, Schlaphoff, Verena, Döhner, Katinka, Vondran, Florian, Sarrazin, Christoph, Manns, Michael P., Pinto Marques Souza de Oliveira, Cláudia, Sodeik, Beate, Ciesek, Sandra, von Hahn, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315608/
https://ncbi.nlm.nih.gov/pubmed/25646622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117152
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