Primary Biliary Acids Inhibit Hepatitis D Virus (HDV) Entry into Human Hepatoma Cells Expressing the Sodium-Taurocholate Cotransporting Polypeptide (NTCP)

BACKGROUND: The sodium-taurocholate cotransporting polypeptide (NTCP) is both a key bile acid (BA) transporter mediating uptake of BA into hepatocytes and an essential receptor for hepatitis B virus (HBV) and hepatitis D virus (HDV). In this study we aimed to characterize to what extent and through...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Veloso Alves Pereira, Isabel, Buchmann, Bettina, Sandmann, Lisa, Sprinzl, Kathrin, Schlaphoff, Verena, Döhner, Katinka, Vondran, Florian, Sarrazin, Christoph, Manns, Michael P., Pinto Marques Souza de Oliveira, Cláudia, Sodeik, Beate, Ciesek, Sandra, von Hahn, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315608/
https://ncbi.nlm.nih.gov/pubmed/25646622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117152
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