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Homologous Recombination DNA Repair Genes Play a Critical Role in Reprogramming to a Pluripotent State
Induced pluripotent stem (iPS) cells hold great promise for personalized regenerative medicine. However, recent studies show iPS cell lines carry genetic abnormalities, suggesting reprogramming may be mutagenic. Here we show that ectopic expression of the reprogramming factors increases the levels o...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4315363/ https://ncbi.nlm.nih.gov/pubmed/23478019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.02.005 |
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