Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks

We introduce a method for simultaneous prediction of microRNA–target interactions and their mediated competitive endogenous RNA (ceRNA) interactions. Using high-throughput validation assays in breast cancer cell lines, we show that our integrative approach significantly improves on microRNA–target p...

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Опубликовано в: :Genome Res
Главные авторы: Chiu, Hua-Sheng, Llobet-Navas, David, Yang, Xuerui, Chung, Wei-Jen, Ambesi-Impiombato, Alberto, Iyer, Archana, Kim, Hyunjae Ryan, Seviour, Elena G., Luo, Zijun, Sehgal, Vasudha, Moss, Tyler, Lu, Yiling, Ram, Prahlad, Silva, José, Mills, Gordon B., Califano, Andrea, Sumazin, Pavel
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2015
Предметы:
Method
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315299/
https://ncbi.nlm.nih.gov/pubmed/25378249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.178194.114
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