The number of titrated microRNA species dictates ceRNA regulation

microRNAs (miRNAs) play key roles in cancer, but their propensity to couple their targets as competing endogenous RNAs (ceRNAs) has only recently emerged. Multiple models have studied ceRNA regulation, but these models did not account for the effects of co-regulation by miRNAs with many targets. We...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Chiu, Hua-Sheng, Martínez, María Rodríguez, . Komissarova, Elena V, Llobet-Navas, David, Bansal, Mukesh, Paull, Evan O, Silva, José, Yang, Xuerui, Sumazin, Pavel, Califano, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Computational Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961349/
https://ncbi.nlm.nih.gov/pubmed/29684207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky286
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