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Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development
Transforming growth factor-beta3 (TGF-β3) plays a critical role in palatal epithelial cells by inducing palatal epithelial fusion, failure of which results in cleft palate, one of the most common birth defects in humans. Recent studies have shown that Smad-dependent and Smad-independent pathways wor...
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| Veröffentlicht in: | Dev Biol |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4314443/ https://ncbi.nlm.nih.gov/pubmed/25523394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.12.006 |
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