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Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development

Transforming growth factor-beta3 (TGF-β3) plays a critical role in palatal epithelial cells by inducing palatal epithelial fusion, failure of which results in cleft palate, one of the most common birth defects in humans. Recent studies have shown that Smad-dependent and Smad-independent pathways wor...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Lane, Jamie, Yumoto, Kenji, Azhar, Mohamad, Ninomiya-Tsuji, Jun, Inagaki, Maiko, Hu, Yingling, Deng, Chu-Xia, Kim, Jieun, Mishina, Yuji, Kaartinen, Vesa
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314443/
https://ncbi.nlm.nih.gov/pubmed/25523394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.12.006
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