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Biocompatible Infinite Coordination Polymer Nanoparticle –Nucleic Acid Conjugates For Antisense Gene Regulation

Herein, we report the synthesis of DNA-functionalized infinite coordination polymer (ICP) nanoparticles as biocompatible gene regulation agents. ICP nanoparticles were synthesized from ferric nitrate and a ditopic 3-hydroxy-4-pyridinone (HOPO) ligand bearing a pendant azide. Addition of Fe(III) to a...

詳細記述

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書誌詳細
出版年:Angew Chem Int Ed Engl
主要な著者: Calabrese, Colin M., Merkel, Timothy J., Briley, William E., Randeria, Pratik S., Narayan, Suguna P., Rouge, Jessica L., Walker, David A., Scott, Alexander W., Mirkin, Chad A.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314394/
https://ncbi.nlm.nih.gov/pubmed/25393766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201407946
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