Targeted sequencing using a 47 gene multiple myeloma mutation panel (M(3)P) in -17p high risk disease

We constructed a multiple myeloma (MM)-specific gene panel for targeted sequencing and investigated 72 untreated high-risk (del17p) MM patients. Mutations were identified in 78% of the patients. While the majority of studied genes were mutated at similar frequency to published literature, the preval...

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Библиографические подробности
Опубликовано в: :Br J Haematol
Главные авторы: Kortüm, Klaus M., Langer, Christian, Monge, Jorge, Bruins, Laura, Egan, Jan B., Zhu, Yuan X., Shi, Chang Xin, Jedlowski, Patrick, Schmidt, Jessica, Ojha, Juhi, Bullinger, Lars, Liebisch, Peter, Kull, Miriam, Champion, Mia D., Van Wier, Scott, Ahmann, Gregory, Rasche, Leo, Knop, Stefan, Fonseca, Rafael, Einsele, Hermann, Stewart, A Keith, Braggio, Esteban
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314325/
https://ncbi.nlm.nih.gov/pubmed/25302557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13171
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