Targeted sequencing using a 47 gene multiple myeloma mutation panel (M(3)P) in -17p high risk disease

We constructed a multiple myeloma (MM)-specific gene panel for targeted sequencing and investigated 72 untreated high-risk (del17p) MM patients. Mutations were identified in 78% of the patients. While the majority of studied genes were mutated at similar frequency to published literature, the preval...

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Pubblicato in:Br J Haematol
Autori principali: Kortüm, Klaus M., Langer, Christian, Monge, Jorge, Bruins, Laura, Egan, Jan B., Zhu, Yuan X., Shi, Chang Xin, Jedlowski, Patrick, Schmidt, Jessica, Ojha, Juhi, Bullinger, Lars, Liebisch, Peter, Kull, Miriam, Champion, Mia D., Van Wier, Scott, Ahmann, Gregory, Rasche, Leo, Knop, Stefan, Fonseca, Rafael, Einsele, Hermann, Stewart, A Keith, Braggio, Esteban
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314325/
https://ncbi.nlm.nih.gov/pubmed/25302557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13171
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