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Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function
SR family RNA binding proteins regulate splicing of nascent RNAs in vitro but their physiological role in vivo is largely unexplored, as genetic deletion of many SR protein genes results in embryonic lethality. Here we show that SRSF3HKO mice carrying a hepatocyte-specific deletion of Srsf3 (homolog...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4314219/ https://ncbi.nlm.nih.gov/pubmed/23299886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2342 |
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