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Splicing factor SRSF3 is crucial for hepatocyte differentiation and metabolic function

SR family RNA binding proteins regulate splicing of nascent RNAs in vitro but their physiological role in vivo is largely unexplored, as genetic deletion of many SR protein genes results in embryonic lethality. Here we show that SRSF3HKO mice carrying a hepatocyte-specific deletion of Srsf3 (homolog...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sen, Supriya, Jumaa, Hassan, Webster, Nicholas J.G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314219/
https://ncbi.nlm.nih.gov/pubmed/23299886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2342
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