Molecular mechanisms governing different pharmacokinetics of ginsenosides and potential for ginsenoside-perpetrated herb–drug interactions on OATP1B3

BACKGROUND AND PURPOSE: Ginsenosides are bioactive saponins derived from Panax notoginseng roots (Sanqi) and ginseng. Here, the molecular mechanisms governing differential pharmacokinetics of 20(S)-protopanaxatriol-type ginsenoside Rg(1), ginsenoside Re and notoginsenoside R(1) and 20(S)-protopanaxa...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Jiang, Rongrong, Dong, Jiajia, Li, Xiuxue, Du, Feifei, Jia, Weiwei, Xu, Fang, Wang, Fengqing, Yang, Junling, Niu, Wei, Li, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314195/
https://ncbi.nlm.nih.gov/pubmed/25297453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12971
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