Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardized Ginkgo biloba leaf extracts to rats via different routes of administration

BACKGROUND AND PURPOSE: Flavonols and terpene lactones are putatively responsible for the properties of Ginkgo biloba leaf extracts that relate to prevention and treatment of cardiovascular disease and cerebral insufficiency. Here, we characterized rat systemic and cerebral exposure to these ginkgo...

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Main Authors: Chen, Feng, Li, Li, Xu, Fang, Sun, Yan, Du, Feifei, Ma, Xutao, Zhong, Chenchun, Li, Xiuxue, Wang, Fengqing, Zhang, Nating, Li, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834766/
https://ncbi.nlm.nih.gov/pubmed/23808355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12285
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