Rapid and Sensitive RT-QuIC Detection of Human Creutzfeldt-Jakob Disease Using Cerebrospinal Fluid

Fast, definitive diagnosis of Creutzfeldt-Jakob disease (CJD) is important in assessing patient care options and transmission risks. Real-time quaking-induced conversion (RT-QuIC) assays of cerebrospinal fluid (CSF) and nasal-brushing specimens are valuable in distinguishing CJD from non-CJD conditi...

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Detalles Bibliográficos
Publicado en:mBio
Autores principales: Orrú, Christina D., Groveman, Bradley R., Hughson, Andrew G., Zanusso, Gianluigi, Coulthart, Michael B., Caughey, Byron
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313917/
https://ncbi.nlm.nih.gov/pubmed/25604790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02451-14
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