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Integrative analysis of sequencing and array genotype data for discovering disease associations with rare mutations
In the large cohorts that have been used for genome-wide association studies (GWAS), it is prohibitively expensive to sequence all cohort members. A cost-effective strategy is to sequence subjects with extreme values of quantitative traits or those with specific diseases. By imputing the sequencing...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4313847/ https://ncbi.nlm.nih.gov/pubmed/25583502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406143112 |
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