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MaCH: Using Sequence and Genotype Data to Estimate Haplotypes and Unobserved Genotypes

Genome-wide association studies (GWAS) can identify common alleles that contribute to complex disease susceptibility. Despite the large number of SNPs assessed in each study, the effects of most common SNPs must be evaluated indirectly using either genotyped markers or haplotypes thereof as proxies....

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Main Authors: Li, Yun, Willer, Cristen J., Ding, Jun, Scheet, Paul, Abecasis, Gonçalo R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175618/
https://ncbi.nlm.nih.gov/pubmed/21058334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20533
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