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Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABA(A) receptors

GABA(A)-receptor-based interneuron circuitry is essential for higher order function of the human nervous system and is implicated in schizophrenia, depression, anxiety disorders, and autism. Here we demonstrate that giant ankyrin-G (480-kDa ankyrin-G) promotes stability of somatodendritic GABAergic...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Tseng, Wei Chou, Jenkins, Paul M., Tanaka, Masashi, Mooney, Richard, Bennett, Vann
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313813/
https://ncbi.nlm.nih.gov/pubmed/25552561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417989112
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