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Giant ankyrin-G stabilizes somatodendritic GABAergic synapses through opposing endocytosis of GABA(A) receptors
GABA(A)-receptor-based interneuron circuitry is essential for higher order function of the human nervous system and is implicated in schizophrenia, depression, anxiety disorders, and autism. Here we demonstrate that giant ankyrin-G (480-kDa ankyrin-G) promotes stability of somatodendritic GABAergic...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4313813/ https://ncbi.nlm.nih.gov/pubmed/25552561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417989112 |
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