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Reduced autophagy in livers of fasted, fat-depleted, ghrelin-deficient mice: Reversal by growth hormone

Plasma growth hormone (GH) and hepatic autophagy each have been reported to protect against hypoglycemia in the fasted state, but previous data have not linked the two. Here we demonstrate a connection using a mouse model of fasting in a fat-depleted state. Mice were subjected to 1 wk of 60% calorie...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Zhang, Yuanyuan, Fang, Fei, Goldstein, Joseph L., Brown, Michael S., Zhao, Tong-Jin
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313810/
https://ncbi.nlm.nih.gov/pubmed/25583513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423643112
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