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Growth hormone acts on liver to stimulate autophagy, support glucose production, and preserve blood glucose in chronically starved mice

When mice are subjected to 60% calorie restriction for several days, they lose nearly all of their body fat. Although the animals lack energy stores, their livers produce enough glucose to maintain blood glucose at viable levels even after a 23-hour fast. This adaptation is mediated by a marked incr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fang, Fei, Shi, Xuanming, Brown, Michael S., Goldstein, Joseph L., Liang, Guosheng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6462072/
https://ncbi.nlm.nih.gov/pubmed/30910968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901867116
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