Free radical adducts induce alterations in DNA cytosine methylation.
Methylation of cytosines in DNA is important for the regulation of expression of many genes. During carcinogenesis, normal patterns of gene methylation can be altered. Oxygen radical injury, shown to damage DNA in a variety of ways associated with cancer development and other conditions, has been su...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43137/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8108398/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1261 |
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