Mutational Analysis of Pneumocystis jirovecii Dihydropteroate Synthase and Dihydrofolate Reductase Genes in HIV-Infected Patients in China

We investigated Pneumocystis jirovecii dihydropteroate synthase (DHPS) and dihydrofolate reductase (DHFR) genes for mutations in 25 Chinese HIV-infected patients with P. jirovecii pneumonia. We identified DHPS mutations in 3 (12%) patients and DHFR mutations in 1 (4%) patient. The prevalence of DHPS...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Deng, Xilong, Zhuo, Li, Lan, Yun, Dai, Zhaoxia, Chen, Wan-shan, Cai, Weiping, Kovacs, Joseph A., Ma, Liang, Tang, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Mycology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313241/
https://ncbi.nlm.nih.gov/pubmed/25122865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01848-14
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