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Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator".

An accurate assay of diadenosine 5',5'''- P1,P4-tetraphosphate [A(5') pppp(5')A], which was shown to be formed in vitro in the backreaction of the amino acid activation step, has been developed in various cell lines in culture and in normal mouse liver or hepatoma in vivo. Use of radioactive labelin...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Rapaport, E, Zamecnik, P C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1069282/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.11.3984
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